CEREBROTENDINOUS XANTHOMATOSIS: A PRACTICE REVIEW OF PATHOPHYSIOLOGY, DIAGNOSIS, AND TREATMENT

Cerebrotendinous Xanthomatosis Moisturiser represents a rare and underdiagnosed inherited neurometabolic disorder due to homozygous or compound heterozygous variants involving the CYP27A1 gene.This bile acid metabolism disorder represents a key potentially treatable neurogenetic condition due to the wide spectrum of neurological presentations in wh

Background: The head and neck squamous cell carcinomas (HNSCC) is one of the most frequent cancers in the world, with an unfavorable prognosis.Cancer stem cells (CSCs) have been found to be responsible for HNSCC recurrence and therapeutic resistance.Methods: The stemness of HNSCC was measured using a stemness index based on mRNA expression (mRNAsi)